Cynthia Levy Selected Research

Ursodeoxycholic Acid (Urso)

1/2022	Proof-of-concept study to evaluate the safety and efficacy of saroglitazar in patients with primary biliary cholangitis.
1/2022	A phase II, randomized, open-label, 52-week study of seladelpar in patients with primary biliary cholangitis.
8/2021	Impact of Obeticholic acid Exposure on Decompensation and Mortality in Primary Biliary Cholangitis and Cirrhosis.
1/2021	Combination of fibrates with obeticholic acid is able to normalise biochemical liver tests in patients with difficult-to-treat primary biliary cholangitis.
1/2021	A randomized placebo-controlled trial of elafibranor in patients with primary biliary cholangitis and incomplete response to UDCA.
1/2021	Oral Vancomycin or Ursodeoxycholic Acid for Pediatric Primary Sclerosing Cholangitis? The Uncontroversial Need for Randomized Controlled Trials.
1/2021	Fibrates for the Treatment of Primary Biliary Cholangitis Unresponsive to Ursodeoxycholic Acid: An Exploratory Study.
1/2021	Ursodeoxycholic Acid Response Is Associated With Reduced Mortality in Primary Biliary Cholangitis With Compensated Cirrhosis.
12/2020	Hispanic Patients with Primary Biliary Cholangitis Have Decreased Access to Care Compared to Non-Hispanics.
2/2020	Methylation signatures in peripheral blood are associated with marked age acceleration and disease progression in patients with primary sclerosing cholangitis.

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Cynthia Levy Research Topics

Disease

30	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 01/2022 - 12/2003
15	Fibrosis (Cirrhosis) 01/2022 - 09/2009
15	Liver Diseases (Liver Disease) 01/2022 - 11/2004
14	Sclerosing Cholangitis 01/2021 - 11/2011
13	Pruritus (Itching) 01/2022 - 04/2003
7	Autoimmune Hepatitis 01/2022 - 02/2006
5	Disease Progression 01/2022 - 09/2009
5	Cholestasis 01/2022 - 05/2003
5	Liver Cirrhosis (Hepatic Cirrhosis) 01/2021 - 01/2016
5	Hepatitis C 03/2020 - 02/2009
5	End Stage Liver Disease 01/2018 - 12/2003
4	Hepatocellular Carcinoma (Hepatoma) 01/2021 - 08/2013
4	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2021 - 01/2020
4	Cholangitis 02/2020 - 08/2015
4	Neoplasms (Cancer) 01/2020 - 08/2013
3	Fatigue 01/2022 - 04/2003
3	Liver Failure 09/2014 - 05/2003
3	Non-alcoholic Fatty Liver Disease 08/2013 - 03/2007
2	Acute Intermittent Porphyria (Porphyria, Acute) 07/2022 - 01/2020
2	Inflammation (Inflammations) 01/2022 - 01/2021
2	Portal Hypertension 01/2021 - 05/2018
2	Osteoporosis 12/2003 - 04/2003
1	Polyneuropathies (Polyneuropathy) 07/2022
1	COVID-19 01/2022
1	Hepatic Encephalopathy 01/2022
1	Polyps 01/2020
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 03/2019
1	Autoimmune Diseases (Autoimmune Disease) 01/2019
1	Sarcoidosis (Schaumann Disease) 01/2019
1	Pathologic Constriction (Stenosis) 06/2018
1	Myalgia 10/2017
1	Spasm (Spasms) 10/2017
1	Dizziness (Lightheadedness) 10/2017

Drug/Important Bio-Agent (IBA)

20	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 01/2022 - 05/2003
7	Alkaline PhosphataseIBA 01/2022 - 01/2018
7	Bile Acids and Salts (Bile Acids)IBA 01/2022 - 01/2016
5	Fibric Acids (Fibrates)IBA 01/2021 - 09/2017
4	obeticholic acidIBA 08/2021 - 01/2018
3	seladelparIBA 01/2022 - 10/2017
3	Mycophenolic Acid (Cellcept)FDA LinkGeneric 01/2022 - 03/2002
3	Antiviral Agents (Antivirals)IBA 03/2020 - 09/2009
3	Cholestyramine Resin (Questran)FDA LinkGeneric 12/2003 - 04/2003
2	Heme (Haem)IBA 07/2022 - 01/2020
2	Tacrolimus (Prograf)FDA LinkGeneric 01/2022 - 03/2002
2	Pharmaceutical PreparationsIBA 08/2021 - 05/2003
2	Narcotic Antagonists (Opioid Antagonists)IBA 01/2021 - 12/2003
2	Biological ProductsIBA 01/2021 - 11/2004
2	CollagenIBA 01/2021 - 02/2020
2	Azathioprine (Imuran)FDA LinkGeneric 01/2019 - 03/2002
2	Fenofibrate (CiL)FDA LinkGeneric 01/2019 - 06/2015
2	Cyclosporine (Ciclosporin)FDA LinkGeneric 01/2010 - 03/2002
2	CalciumIBA 12/2003 - 04/2003
2	Vitamin D FDA LinkGeneric 12/2003 - 04/2003
1	Hemin (Panhematin)FDA Link 07/2022
1	AntibodiesIBA 01/2022
1	saroglitazarIBA 01/2022
1	alpha-Fetoproteins (alpha-Fetoprotein)IBA 01/2022
1	Biomarkers (Surrogate Marker)IBA 01/2022
1	Oxygen (Dioxygen)IBA 01/2022
1	GlucocorticoidsIBA 01/2022
1	PPAR deltaIBA 01/2022
1	Vancomycin FDA LinkGeneric 01/2021
1	RNA (Ribonucleic Acid)IBA 01/2021
1	Opioid Analgesics (Opioids)IBA 01/2021
1	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 01/2021
1	cenicrivirocIBA 01/2021
1	CC ChemokinesIBA 01/2021
1	Histamine Antagonists (Antihistamines)IBA 01/2021
1	Interleukin-8 (Interleukin 8)IBA 01/2021
1	Butorphanol (BC 2627)FDA LinkGeneric 01/2021
1	2- (2,6- dimethyl- 4- (3- (4- (methylthio)phenyl)- 3- oxo- 1- propenyl)phenoxyl)- 2- methylpropanoic acidIBA 01/2021
1	Antinuclear AntibodiesIBA 10/2020
1	gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA 02/2020
1	Alanine Transaminase (SGPT)IBA 02/2020
1	vedolizumabIBA 01/2020
1	IntegrinsIBA 01/2020
1	Tumor Necrosis Factor InhibitorsIBA 01/2020
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2020
1	maralixibatIBA 03/2019
1	sodium-bile acid cotransporterIBA 03/2019
1	simtuzumabIBA 01/2019
1	Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA 01/2019
1	AntigensIBA 01/2019
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2019
1	Abatacept (Orencia)FDA Link 01/2019
1	synthetic preimplantation factorIBA 10/2018
1	BezafibrateIBA 01/2018
1	Anti-Bacterial Agents (Antibiotics)IBA 11/2017
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 10/2017

Therapy/Procedure

24	Therapeutics 01/2021 - 03/2002
19	Liver Transplantation 01/2022 - 12/2003
7	Transplantation 08/2021 - 12/2003
2	Aftercare (After-Treatment) 01/2021 - 01/2021
1	Artificial Respiration (Mechanical Ventilation) 01/2022
1	Cannula 01/2022
1	Patient Transfer (Patient Dumping) 01/2022
1	Patient Readmission 01/2022
1	Off-Label Use 01/2021
1	Cholecystectomy 01/2020
1	Subcutaneous Injections 01/2019